Structure of PDB 4zvp Chain B

Receptor sequence
>4zvpB (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
YKIPVEADFLFAYSTVPGYVSMRSPGRGSWFVQALCSILEEHGKDLEIMQ
ILTRVNDRVARHFESCSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB4zvp Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
ChainB
Resolution2.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S231 M232 R233 P235 S275 C276 S21 M22 R23 P25 S65 C66
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4zvp, PDBe:4zvp, PDBj:4zvp
PDBsum4zvp
PubMed27032039
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

[Back to BioLiP]