Structure of PDB 4zq9 Chain B

Receptor sequence
>4zq9B (length=189) Species: 648242 (Adeno-associated virus 2 Srivastava/1982) [Search protein sequence]
PGFYEIVIKVPSDLDGISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTV
AEKLQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVL
GRFLSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPN
FLLPKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHLT
3D structure
PDB4zq9 Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B V104 R107 R138 V99 R102 R133 PDBbind-CN: Kd=128nM
BS02 dna B S102 M103 G106 K136 R138 G142 G143 G144 N145 S97 M98 G101 K131 R133 G137 G138 G139 N140 PDBbind-CN: Kd=128nM
External links
PDB RCSB:4zq9, PDBe:4zq9, PDBj:4zq9
PDBsum4zq9
PubMed26370092
UniProtP03132|REP68_AAV2S Protein Rep68 (Gene Name=Rep68)

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