Structure of PDB 4zpr Chain B

Receptor sequence
>4zprB (length=279) Species: 10090 (Mus musculus) [Search protein sequence]
SERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTI
SYLRVRKLLDCFYLKALDGFVMVLTDDGDMVYISDNVNKYMGLTQFELTG
HSVFDFTHPCDHEEMREMLTTQRSFFLRMKCTLTRTMNIKSATWKVLHCT
GHIHCLVLICEPIPHPSNIESKTFLSRHSLDMKFSYCDITELMGYEPEEL
LGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQ
ATVIYNTKNSQPQCIVCVNYVVSGIIQHD
3D structure
PDB4zpr Structural integration in hypoxia-inducible factors.
ChainB
Resolution3.902 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R18 K21 R29 N183 R4 K7 R15 N138
BS02 dna B S22 R23 R27 R30 D55 K56 S8 R9 R13 R16 D41 K42
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:4zpr, PDBe:4zpr, PDBj:4zpr
PDBsum4zpr
PubMed26245371
UniProtQ61221|HIF1A_MOUSE Hypoxia-inducible factor 1-alpha (Gene Name=Hif1a)

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