Structure of PDB 4znx Chain B

Receptor sequence
>4znxB (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPS
NYVAPV
3D structure
PDB4znx The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y91 Y93 D100 E116 G117 D118 W119 P134 N136 Y137 Y6 Y8 D15 E31 G32 D33 W34 P49 N51 Y52
BS02 peptide B W120 S135 P140 W35 S50 P55
External links
PDB RCSB:4znx, PDBe:4znx, PDBj:4znx
PDBsum4znx
PubMed27599862
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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