Structure of PDB 4znu Chain B

Receptor sequence
>4znuB (length=226) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKG
MEHLYSMVVPLSDLLLEMLDAHRLHA
3D structure
PDB4znu Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E542 I49 K53 L63 V67 L70 E217
BS02 4Q9 B M343 L346 T347 A350 E353 L387 L391 F404 V418 E419 M421 I424 G521 H524 L525 M34 L37 T38 A41 E44 L78 L82 F95 V109 E110 M112 I115 G200 H203 L204
External links
PDB RCSB:4znu, PDBe:4znu, PDBj:4znu
PDBsum4znu
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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