Structure of PDB 4zns Chain B

Receptor sequence
>4znsB (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKVVPLSDLLLEMLDAHRL
3D structure
PDB4zns Predictive features of ligand-specific signaling through the estrogen receptor.
ChainB
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 L372 V376 L379 E380 D538 E542 I53 L67 V71 L74 E75 D225 E229
BS02 OFB B M343 T347 E353 L387 L391 F404 V418 M421 I424 H524 L525 M528 M38 T42 E48 L82 L86 F99 V113 M116 I119 H214 L215 M218
External links
PDB RCSB:4zns, PDBe:4zns, PDBj:4zns
PDBsum4zns
PubMed27107013
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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