Structure of PDB 4zir Chain B

Receptor sequence
>4zirB (length=247) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
SGRIELNSVSFRYNGDYVLKDVNAEFETGKIYVVVGKNGSGKTTLLKILA
GLLAAAGEIFLDGSPADPFLLRKNVGYVFQNPSSQIIGATVEEDVAFSLE
IDESEMRKRIKKVLELVGLSGLAAADPLNLSGGQKQRLAIASMLARDTRF
LALDEPVSMLDPPSQREIFQVLESLKNEGKGIILVTHELEYLDDMDFILH
ISNGTIDFCGSWEEFVEREFDDVEIPFKWKLWKKCGKINLWEDRYEN
3D structure
PDB4zir ATP binding drives substrate capture in an ECF transporter by a release-and-catch mechanism.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.-.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ANP B N131 S133 G134 G135 N129 S131 G132 G133
BS02 MG B T42 Q79 T43 Q80
BS03 ANP B Y12 V17 N37 G38 G40 K41 T42 T43 Q79 Y13 V18 N38 G39 G41 K42 T43 T44 Q80
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0032217 riboflavin transmembrane transporter activity
GO:0042626 ATPase-coupled transmembrane transporter activity
Biological Process
GO:0032218 riboflavin transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex

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Cellular Component
External links
PDB RCSB:4zir, PDBe:4zir, PDBj:4zir
PDBsum4zir
PubMed26052893
UniProtQ9X1Z1|ECFA1_THEMA Energy-coupling factor transporter ATP-binding protein EcfA1 (Gene Name=ecfA1)

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