Structure of PDB 4zi8 Chain B

Receptor sequence

>4zi8B (length=323) Species: 10090 (Mus musculus) [Search protein sequence]

HENLYFQGSTIIHYEILEERERGFPVGNVVTDLGLDLGSLSARRLRVVSG
ASRRFFEVNWETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSA
EVVVQDINDNNPSFPTGEMKLEISEALAPGTRFPLESAHDPDVGSNSLQT
YELSHNEYFALRVQTREDGTKYAELVLERALDWEREPSVQLVLTALDGGT
PARSATLPIRITVLDANDNAPAFNQSLYRARVREDAPPGTRVAQVLATDL
DEGLNGEIVYSFGSHNRAGVRELFALDLVTGVLTIKGRLDFEDTKLHEIY
IQAKDKGANPEGAHCKVLVEVVD

3D structure

PDB

4zi8 Structure and Sequence Analyses of Clustered Protocadherins Reveal Antiparallel Interactions that Mediate Homophilic Specificity.

Chain

Resolution

1.698 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	CA	B	N99 N101 D131 D133 N137 D188	N108 N110 D140 D142 N146 D197
BS02	CA	B	E9 E65 D97 I98 D100 D133	E18 E74 D106 I107 D109 D142
BS03	CA	B	E9 E10 D63 E65 D100	E18 E19 D72 E74 D109
BS04	CA	B	E116 E175 D206 A207 D209 D242	E125 E184 D215 A216 D218 D251
BS05	CA	B	E116 D173 E175 D209	E125 D182 E184 D218
BS06	CA	B	N208 N210 D240 D242 N246 D296	N217 N219 D249 D251 N255 D305

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4zi8, PDBe:4zi8, PDBj:4zi8
PDBsum	4zi8
PubMed	26481813
UniProt	Q91XX1

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