Structure of PDB 4zg4 Chain B

Receptor sequence
>4zg4B (length=705) Species: 9606 (Homo sapiens) [Search protein sequence]
MAVAELYTQYNRVWIPDPEEVWKSAEIAKDYRVGKVLRLLLEDGELDYSV
NPESLPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSG
IILVAMNPYKQLPIYGDAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNN
RNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSHVEDKVLASNPITEAV
GNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVFQSENE
RNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMV
ETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSH
LKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKK
IYAHLFDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINY
ANEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKMGIL
ELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSNTSFVIQHFADK
VEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENRTTVGSKFRSS
LYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRI
SAQSYPSRYIEFYSRYKKEVCKVVLHRLIQDSNQYQFGKTKIFFRGQVAY
LEKLR
3D structure
PDB4zg4 Force-producing ADP state of myosin bound to actin.
ChainB
Resolution2.36 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S163 G164 T168 N212 S215 S216 G438 E440
Catalytic site (residue number reindexed from 1) S161 G162 T166 N208 S211 S212 G434 E436
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B T168 S216 T166 S212
BS02 ADP B N109 P110 G164 G166 K167 T168 V169 N212 N107 P108 G162 G164 K165 T166 V167 N208
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4zg4, PDBe:4zg4, PDBj:4zg4
PDBsum4zg4
PubMed26976594
UniProtQ9NQX4|MYO5C_HUMAN Unconventional myosin-Vc (Gene Name=MYO5C)

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