Structure of PDB 4zbn Chain B

Receptor sequence
>4zbnB (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
HPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNSVFKQYFFET
KCRDSGCRGIDSKHWNSYCTTTHTFVKALTMAAWRFIRIDTACVCVLSR
3D structure
PDB4zbn Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor.
ChainB
Resolution2.447 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B I31 K32 W76 F86 F101 R103 I28 K29 W65 F75 F86 R88 PDBbind-CN: Kd=0.21nM
BS02 dna B F7 F12 S19 V20 W21 Y52 F54 R59 R69 F4 F9 S16 V17 W18 Y46 F48 R53 R58 PDBbind-CN: Kd=0.21nM
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding

View graph for
Molecular Function
External links
PDB RCSB:4zbn, PDBe:4zbn, PDBj:4zbn
PDBsum4zbn
PubMed26027732
UniProtP01138|NGF_HUMAN Beta-nerve growth factor (Gene Name=NGF)

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