Structure of PDB 4z7v Chain B

Receptor sequence
>4z7vB (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVTP
LGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTIS
PSLLVCSVTDFYPAQIKVRWFQEETTGVVSTPLIRNGDWTFQILVMLEMR
GDVYTCHVEHPSLQNPIIVEWR
3D structure
PDB4z7v Determinants of Gliadin-Specific T Cell Selection in Celiac Disease.
ChainB
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B F11 G13 C15 L26 Y30 Y37 Y47 A57 Y60 W61 R70 E74 V78 H81 N82 L85 F9 G11 C13 L24 Y28 Y35 Y45 A55 Y58 W59 R68 E72 V76 H79 N80 L83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4z7v, PDBe:4z7v, PDBj:4z7v
PDBsum4z7v
PubMed25948817
UniProtO19707

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