Structure of PDB 4z7u Chain B

Receptor sequence
>4z7uB (length=169) Species: 9606 (Homo sapiens) [Search protein sequence]
DSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVT
PLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTI
SPLLVCSVTDFYPAQIKVRWQEETTGVVSTPLIRNGDWTFQILVMLEMDV
YTCHVEHPSLQNPIIVEWR
3D structure
PDB4z7u Determinants of Gliadin-Specific T Cell Selection in Celiac Disease.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B G13 C15 Y30 Y37 Y47 A57 Y60 W61 R70 E74 V78 H81 N82 L85 G12 C14 Y29 Y36 Y46 A56 Y59 W60 R69 E73 V77 H80 N81 L84
BS02 FUC B N19 T21 N18 T20
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4z7u, PDBe:4z7u, PDBj:4z7u
PDBsum4z7u
PubMed25948817
UniProtO19707

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