Structure of PDB 4yzq Chain B

Receptor sequence

>4yzqB (length=195) Species: 521460 (Caldicellulosiruptor bescii DSM 6725)

GTNTGGVLVITDTIIVKSGQTYDGKGIKIIAQGMGDGSQSENQKPIFKLE
KGANLKNVIIGAPGCDGIHCYGDNVVENVVWEDVGEDALTVKSEGVVEVI
GGSAKEAADAVFNLNAPCTFKVKNFTATNIGKLVRQNGNTTFKVVIYLED
VTLNNVKSCVAKSDSPVSELWYHNLNVNNCKTLFEFPSQSQIHQY

3D structure

• PDB: 4yzq The catalytic mechanism and unique low pH optimum of Caldicellulosiruptor bescii family 3 pectate lyase.
• Chain: B
• Resolution: 1.48 Å

Enzymatic activity

• Enzyme Commision number: 4.2.2.2: pectate lyase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADA	B	D107 K130 R133 K160	D109 K132 R135 K162
BS02	ADA	B	E39 D107 R133 N135 G136	E41 D109 R135 N137 G138
BS03	CA	B	Q37 E84 D107	Q39 E86 D109
BS04	CA	B	E39 E84	E41 E86
BS05	CA	B	D64 E84 D85	D66 E86 D87
BS06	CA	B	D81 V82 E104	D83 V84 E106
BS07	GTR	B	D107 K130 R133 K160	D109 K132 R135 K162
BS08	ADA	B	E39 D107 R133 N135 G136	E41 D109 R135 N137 G138
BS09	ADA	B	E39 D85	E41 D87

Gene Ontology

Molecular Function

• GO:0030570 pectate lyase activity

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:4yzq, PDBe:4yzq, PDBj:4yzq
• PDBsum: 4yzq
• PubMed: 26327384
• UniProt: B9MKT4