Structure of PDB 4ysm Chain B

Receptor sequence
>4ysmB (length=475) Species: 5802 (Eimeria tenella) [Search protein sequence]
DKLAATPGMFVQHSTAAFSDRYKGQRVLGKGSFGEVILCKDKVTGQEYAV
KVISKRQVKQKTDKELLLKEVELLKKLDHPNIMKLYEFFEDKGYFYLVTE
VYTGGELFDEIISRKRFSEVDAARIIRQVLSGITYMHKNKIVHRDLKPEN
LLLENKRKDANIRIIDFGLSTHFESTKKMKDKIGTAYYIAPEVLHGTYDE
KCDVWSTGVILYILLSGCPPFNGANEFDILKKVEKGKFTFDLPQWKKVSE
PAKDLIRKMLAYVPTMRISARDALEHEWLKTTDAATDSIDVPSLESTILN
IRQFQGTQKLAAAALLYMGSKLTTNEETVELNKIFQRMDKNGDGQLDKQE
LMEGYVELMKLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEFVT
VAMDRKTLLSRQRLERAFGMFDADGSGKISSSELATIFGVSEVDSETWRR
VLAEVDRNNDGEVDFEEFRQMLLKL
3D structure
PDB4ysm CDPK is a druggable target in the apicomplexan parasite Eimeria
ChainB
Resolution3.19 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D151 K153 E155 N156 D172 T191
Catalytic site (residue number reindexed from 1) D145 K147 E149 N150 D166 T185
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D345 N347 D349 Q351 E356 D339 N341 D343 Q345 E350
BS02 CA B D392 D394 N396 F398 E400 E403 D386 D388 N390 F392 E394 E397
BS03 CA B D428 D430 S432 K434 E439 D422 D424 S426 K428 E433
BS04 CA B D462 N464 D466 E468 E473 D456 N458 D460 E462 E467
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004683 calcium/calmodulin-dependent protein kinase activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0009931 calcium-dependent protein serine/threonine kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0016310 phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0035556 intracellular signal transduction
GO:0046777 protein autophosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4ysm, PDBe:4ysm, PDBj:4ysm
PDBsum4ysm
PubMed
UniProtQ3HNM4

[Back to BioLiP]