Structure of PDB 4ypi Chain B

Receptor sequence
>4ypiB (length=347) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
RVIPVYQVNNLEEICQLIIQAFEAGVDFQESADSFLLMLCLHHAYQGDYK
LFLESGAVKYLEGHGFRFEVKKRDGVKRLEELLPAVSSGKNIKRTLAAMP
EEETTEANAGQFLSFASLFLPKLVVGEKACLEKVQRQIQVHAEQGLIQYP
TAWQSVGHMMVIFRLMRTNFLIKFLLIHQGMHMVAGHDANDAVISNSVAQ
ARFSGLLIVKTVLDHILQKTERGVRLHPLARTAKVKNEVNSFKAALSSLA
KHGEYAPFARLLNLSGVNNLEHGLFPQLSAIALGVATAHGSTLAGVNVGE
QYQQLREAATEAEKQLQQYAESRELDHLGLDDQEKKILMNFHQKKNE
3D structure
PDB4ypi An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
ChainB
Resolution3.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B R240 F241 K248 D252 H253 L255 Q256 K257 L264 R269 K274 K281 L284 L287 A288 G291 E292 A294 H327 Q355 A358 E359 R202 F203 K210 D214 H215 L217 Q218 K219 L226 R231 K236 K243 L246 L249 A250 G253 E254 A256 H289 Q317 A320 E321
Gene Ontology
Biological Process
GO:0019074 viral RNA genome packaging
Cellular Component
GO:0019013 viral nucleocapsid

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4ypi, PDBe:4ypi, PDBj:4ypi
PDBsum4ypi
PubMed25865894
UniProtP18272|NCAP_EBOZM Nucleoprotein (Gene Name=NP)

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