Structure of PDB 4yp7 Chain B

Receptor sequence
>4yp7B (length=168) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence]
TMRGLLVGRMQPFHRGHLQVIKSILEEVDELIICIGSAQLSHSIEDPFTA
GERVMMLTKALSENGIPASRYYIIPVQDIECNALWVGHIKMLTPPFDRVY
SGNPLVQRLFSEDGYEVTAPPLFYRDRYSGTEVRRRMLDDGDWRSLLPES
VVEVIDEINGVERIKHLA
3D structure
PDB4yp7 Nicotinamide mononucleotide adenylyltransferase displays alternate binding modes for nicotinamide nucleotides.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.1: nicotinamide-nucleotide adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B V9 R11 H16 H19 G38 S39 D80 I81 N84 W87 N105 F125 Y126 S131 G132 V7 R9 H14 H17 G36 S37 D78 I79 N82 W85 N103 F123 Y124 S129 G130
Gene Ontology
Molecular Function
GO:0000309 nicotinamide-nucleotide adenylyltransferase activity
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009435 NAD biosynthetic process
GO:0019363 pyridine nucleotide biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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External links
PDB RCSB:4yp7, PDBe:4yp7, PDBj:4yp7
PDBsum4yp7
PubMed26457427
UniProtO26253|NADM_METTH Nicotinamide-nucleotide adenylyltransferase (Gene Name=MTH_150)

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