Structure of PDB 4yof Chain B

Receptor sequence
>4yofB (length=141) Species: 83331 (Mycobacterium tuberculosis CDC1551) [Search protein sequence]
DLEATLRAIVHSATSLVDARYGAMEVHDRQHRVLHFVYEGIDEETVRRIG
HLPKGLGVIGLLIEDPKPLRLDDVSAHPASIGFPPYHPPMRTFLGVPVRV
RDESFGTLYLTDKTNGQPFSDDDEVLVQALAAAAGIAVANA
3D structure
PDB4yof Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM B Y83 G84 F98 Y100 I103 H113 P115 K116 G117 L118 S142 I143 G144 F145 P146 H149 M152 F155 Y171 T173 Y21 G22 F36 Y38 I41 H51 P53 K54 G55 L56 S80 I81 G82 F83 P84 H87 M90 F93 Y109 T111
External links
PDB RCSB:4yof, PDBe:4yof, PDBj:4yof
PDBsum4yof
PubMed25670859
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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