Structure of PDB 4ymg Chain B

Receptor sequence
>4ymgB (length=239) [Search protein sequence]
LGSILPFNEETADRVSAYCEKNSHGIPDALVEHWEWTRTRFPDADKMSSR
LQGSWMIFTARDRKPKRILEIGCYSGYSALAWYEGTRDTKAEIVTLEYSP
KMIAASREAFKKYGVGDRVKLIEGPAENTLKTLEGEFDLIFVDANKDGYA
GYVKTILDQGLLSANGIILCDNVFARGLTIGPDCAPWLNDHVRPYWNGCG
QALDKFSAGLMEDPRIDVLLLPVFDGVTQIRWKDGAQRA
3D structure
PDB4ymg Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
ChainB
Resolution1.899 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D144 K147 D172 N173
Catalytic site (residue number reindexed from 1) D143 K146 D171 N172
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM B S49 G73 Y75 S79 E98 Y99 P126 A127 E128 D144 A145 N146 Y153 S48 G72 Y74 S78 E97 Y98 P125 A126 E127 D143 A144 N145 Y152 MOAD: Kd=21uM
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
Biological Process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4ymg, PDBe:4ymg, PDBj:4ymg
PDBsum4ymg
PubMed25979334
UniProtQ9HGR1

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