Structure of PDB 4y0f Chain B

Receptor sequence
>4y0fB (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF
TEYETQVKVMSQRHMIDGRWCDCKLPN
3D structure
PDB4y0f Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
ChainB
Resolution2.648 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B I107 L111 W113 K136 F149 R171 P178 N179 I5 L9 W11 K34 F47 R69 P76 N77
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:4y0f, PDBe:4y0f, PDBj:4y0f
PDBsum4y0f
PubMed26883171
UniProtQ13148|TADBP_HUMAN TAR DNA-binding protein 43 (Gene Name=TARDBP)

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