Structure of PDB 4y00 Chain B

Receptor sequence
>4y00B (length=78) Species: 9606 (Homo sapiens) [Search protein sequence]
TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF
TEYETQVKVMSQRHMIGGRWCDCKLPNS
3D structure
PDB4y00 Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B D105 I107 L109 G110 L111 P112 W113 Q134 K136 G146 F149 R171 L177 P178 N179 D3 I5 L7 G8 L9 P10 W11 Q32 K34 G44 F47 R69 L75 P76 N77
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:4y00, PDBe:4y00, PDBj:4y00
PDBsum4y00
PubMed26883171
UniProtQ13148|TADBP_HUMAN TAR DNA-binding protein 43 (Gene Name=TARDBP)

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