Structure of PDB 4xxd Chain B

Receptor sequence
>4xxdB (length=206) Species: 9606 (Homo sapiens) [Search protein sequence]
VQLVESGGGLVQPGGSLRLSCAASGFTFSRYSMSWVRQAPGKGLELVAQI
NSVGSSTYYPDTVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCASGDY
WGQGTLVTVSSASTKGPSVFPLAPSSGTAALGCLVKDYFPEPVTVSWNSG
ALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKV
DKKVEP
3D structure
PDB4xxd Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
ChainB
Resolution2.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B F27 Y32 S33 Q50 S94 G95 D96 F26 Y31 S32 Q49 S97 G98 D99
External links
PDB RCSB:4xxd, PDBe:4xxd, PDBj:4xxd
PDBsum4xxd
PubMed25880481
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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