Structure of PDB 4xqb Chain B

Receptor sequence
>4xqbB (length=185) Species: 52275 (Human adenovirus D37) [Search protein sequence]
YDTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKY
HIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAY
EKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQE
TGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
3D structure
PDB4xqb Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
ChainB
Resolution1.597 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 425 B Y312 P317 S344 K345 Y132 P137 S164 K165 PDBbind-CN: -logKd/Ki=3.79,Kd=163.4uM
BS02 ZN B H231 E351 H51 E171
Gene Ontology
Biological Process
GO:0007155 cell adhesion
GO:0019058 viral life cycle
GO:0019062 virion attachment to host cell
Cellular Component
GO:0019028 viral capsid

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4xqb, PDBe:4xqb, PDBj:4xqb
PDBsum4xqb
PubMed26177934
UniProtQ64823

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