Structure of PDB 4x5s Chain B

Receptor sequence
>4x5sB (length=223) Species: 309806 (Sulfurihydrogenibium azorense) [Search protein sequence]
HWSYEGENGPENWAKLNPEYFWCNLKNQSPVDISDNYKVHAKLEKLHINY
NKAVNPEIVNNGHTIQVNVLEDFKLNIKGKEYHLKQFHFHAPSEHTVNGK
YYPLEMHLVHKDKDGNIAVIGVFFKEGKANPELDKVFKNALKEEGSKVFD
GSININALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELF
KSIMKHNNNRPTQPINSRYILES
3D structure
PDB4x5s Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense.
ChainB
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H64 H89 H91 E95 H108 T174
Catalytic site (residue number reindexed from 1) H63 H88 H90 E94 H107 T173
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H89 H91 H108 H88 H90 H107
BS02 AZM B H89 V110 L173 T174 T175 H88 V109 L172 T173 T174
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0016836 hydro-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4x5s, PDBe:4x5s, PDBj:4x5s
PDBsum4x5s
PubMed25817590
UniProtC1DTU5

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