Structure of PDB 4x3z Chain B

Receptor sequence
>4x3zB (length=348) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
AMHMLRIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSA
SMDTVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKISGGLRVGAA
VGAAPGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEI
IGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIAD
AAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGE
VILYQGRSYKAYRGMGSLGAMSKLVPEGIEGRIAYKGHLKEIIHQQMGGL
RSCMGLTGSATVEDLRTKAQFVRISGAGMKESHVHDVQITKEAPNYRL
3D structure
PDB4x3z Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with XMP and NAD
ChainB
Resolution1.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XMP B M51 G304 S305 I306 C307 T309 D340 G342 G363 S364 Y387 G389 M390 G391 E417 G418 M52 G179 S180 I181 C182 T184 D215 G217 G238 S239 Y262 G264 M265 G266 E277 G278
BS02 NAD B D250 S252 H253 S256 T309 M390 D125 S127 H128 S131 T184 M265
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4x3z, PDBe:4x3z, PDBj:4x3z
PDBsum4x3z
PubMed
UniProtQ9KTW3

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