Structure of PDB 4x3u Chain B

Receptor sequence
>4x3uB (length=53) Species: 10090 (Mus musculus) [Search protein sequence]
VFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEE
KEE
3D structure
PDB4x3u Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain.
ChainB
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SVR B R20 R22 W32 W35 Y39 S40 T41 W42 H47 R11 R13 W23 W26 Y30 S31 T32 W33 H38 MOAD: ic50=8.1uM
PDBbind-CN: -logKd/Ki=5.09,IC50=8.1uM
BS02 SVR B R20 V21 R11 V12 MOAD: ic50=8.1uM
PDBbind-CN: -logKd/Ki=5.09,IC50=8.1uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4x3u, PDBe:4x3u, PDBj:4x3u
PDBsum4x3u
PubMed25660273
UniProtQ8VDS3|CBX7_MOUSE Chromobox protein homolog 7 (Gene Name=Cbx7)

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