Structure of PDB 4x15 Chain B

Receptor sequence
>4x15B (length=257) Species: 10632 (JC polyomavirus) [Search protein sequence]
VEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPN
RDMLPCYSVARIPLPNLILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNG
AGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVM
NTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNT
ATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQ
LRKRRVK
3D structure
PDB4x15 The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
ChainB
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SIA B L54 K59 S60 N264 S266 S268 Q270 L31 K36 S37 N233 S235 S237 Q239
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:4x15, PDBe:4x15, PDBj:4x15
PDBsum4x15
PubMed25855729
UniProtP03089|VP1_POVJC Major capsid protein VP1

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