Structure of PDB 4x11 Chain B

Receptor sequence
>4x11B (length=256) Species: 804310 (JC polyomavirus type 3) [Search protein sequence]
EVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNK
DMLPCYSVARIPLPNLILMWEAVTLKTEVIGVTTLMNVHSNGQATHDNGA
AKPVQGTSFHFFSVGGEALELQGVVFNYRTTYPDGTIFPKNATVQSQVMN
TEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTA
TTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQL
RKRRVK
3D structure
PDB4x11 The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SIA B K59 S60 N123 N264 S266 S268 K35 S36 N91 N232 S234 S236 PDBbind-CN: -logKd/Ki=2.22,Kd=6mM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:4x11, PDBe:4x11, PDBj:4x11
PDBsum4x11
PubMed25855729
UniProtP90498

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