Structure of PDB 4wyu Chain B

Receptor sequence
>4wyuB (length=201) Species: 9606 (Homo sapiens) [Search protein sequence]
AAALEGPYPVEEIRLPRAGGPLGLSIVGGSDHSSHPFGVQEPGVFISKVL
PRGLAARSGLRVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVRRD
PAPPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPT
GAAGRDGRLRVGLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGF
E
3D structure
PDB4wyu Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B P23 L24 G25 L26 S27 I28 V29 S35 S49 H81 S174 L176 G177 P21 L22 G23 L24 S25 I26 V27 S33 S47 H79 S172 L174 G175
External links
PDB RCSB:4wyu, PDBe:4wyu, PDBj:4wyu
PDBsum4wyu
PubMed25734361
UniProtQ14160|SCRIB_HUMAN Protein scribble homolog (Gene Name=SCRIB)

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