Structure of PDB 4wxl Chain B

Receptor sequence
>4wxlB (length=162) Species: 281310 (Haemophilus influenzae 86-028NP) [Search protein sequence]
NVLIYPDDHLKVVCEPVTEVNDAIRKIVDDMFDTMYQEKGIGLAAPQVDI
LQRIITIDVEGDKQNQFVLINPEILASEGETGIEEGCLSIPGFRALVPRK
EKVTVRALDRDGKEFTLDADGLLAICIQHEIDHLNGILFVDYLSPLKRQR
IKEKLIKYKKQI
3D structure
PDB4wxl Crystal structure of a peptide deformylase from Haemophilus influenzae complex with Actinonin
ChainB
Resolution2.33 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G46 Q51 C91 L92 H133 E134 H137
Catalytic site (residue number reindexed from 1) G42 Q47 C87 L88 H129 E130 H133
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BB2 B K43 G44 I45 G46 Q51 G90 C91 L92 R98 C130 H133 E134 H137 K39 G40 I41 G42 Q47 G86 C87 L88 R94 C126 H129 E130 H133
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4wxl, PDBe:4wxl, PDBj:4wxl
PDBsum4wxl
PubMed
UniProtQ4QMV6|DEF_HAEI8 Peptide deformylase (Gene Name=def)

[Back to BioLiP]