Structure of PDB 4ww0 Chain B

Receptor sequence
>4ww0B (length=425) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
HMAKVYIEPKVTFKDVAGIEEVKEEVKEIIEYLKDPVKFQKLGGRPPKGV
LLYGEPGVGKTLLAKAIAGEAHVPFISVSGSDFVEMFVGVGAARVRDLFE
TAKKHAPCMIFIDEIDAVGRDEREQTLNQLLVEMDGFDTSDGIIVIAATN
RPDILDPALLRPGRFDRQIFIPKPDVRGRYEILKVHARNKKLAKDVDLEF
VARATPGLTGADLENLLNEAALLAARKGKEEITMEEIEEALDRIMTISPK
EKEKIAIHEAGHALMGLVSDDDDKVHKISIIPRGMALEDKHIYDKKDLYN
KILVLLGGRAAEEVFFGKDGITTGAENDLQRATDLAYRMVSMWGMSDKVG
PIAIRDTSPDLLREIDEEVRRIITEQYEKAKAIVEEYKEPLKAVVKKLLE
KETITCEEFVEVFKLYGIELKDKCK
3D structure
PDB4ww0 The structure of Aquifex aeolicus FtsH in the ADP-bound state reveals a C2-symmetric hexamer.
ChainB
Resolution2.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H418 H422 D496 H258 H262 D328
BS02 ADP B A158 G198 V199 G200 K201 T202 L203 H338 G362 A363 E366 A17 G57 V58 G59 K60 T61 L62 H186 G210 A211 E214
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ww0, PDBe:4ww0, PDBj:4ww0
PDBsum4ww0
PubMed26057670
UniProtO67077|FTSH_AQUAE ATP-dependent zinc metalloprotease FtsH (Gene Name=ftsH)

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