Structure of PDB 4wlz Chain B

Receptor sequence
>4wlzB (length=290) Species: 10090 (Mus musculus) [Search protein sequence]
VDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEA
SREVAKALLRELLFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYS
DSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVI
GIAREMQPVYRHTFWQFRHENPKTRVGDPPPEGLPGFNSGVMLLNLEAMR
QSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCT
WNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIP
3D structure
PDB4wlz Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
ChainB
Resolution3.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.62: xylosyl alpha-1,3-xylosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D225 D227 H382 D125 D127 H282
BS02 UDP B M103 T105 D225 L226 D227 N384 M8 T10 D125 L126 D127 N284
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
GO:0035252 UDP-xylosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:4wlz, PDBe:4wlz, PDBj:4wlz
PDBsum4wlz
PubMed26414444
UniProtQ3U4G3|XXLT1_MOUSE Xyloside xylosyltransferase 1 (Gene Name=Xxylt1)

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