Structure of PDB 4wk2 Chain B

Receptor sequence
>4wk2B (length=427) Species: 9606 (Homo sapiens) [Search protein sequence]
NRCLKANAKSCGECIQAGPNCGWCTNSTFLSARCDDLEALKKKGCPPDDI
ENPRGSKDIKKNKNVTNKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKR
AEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSF
VEKTVMPYISTTPAKLRNPCTSEQNCTTPFSYKNVLSLTNKGEVFNELVG
KQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGD
GKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAV
TEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENG
KLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPK
KDSDSFKIRPLGFTEEVEVILQYICEC
3D structure
PDB4wk2 Metal ion and ligand binding of integrin alpha 5 beta 1.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S132 Y133 S134 G223 N224 L225 S227 E229 S115 Y116 S117 G206 N207 L208 S210 E212
BS02 MG B S132 S134 E229 S115 S117 E212
BS03 CA B S134 D137 D138 S117 D120 D121
BS04 CA B E169 N224 D226 P228 E229 E152 N207 D209 P211 E212
External links
PDB RCSB:4wk2, PDBe:4wk2, PDBj:4wk2
PDBsum4wk2
PubMed25475857
UniProtP05556|ITB1_HUMAN Integrin beta-1 (Gene Name=ITGB1)

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