Structure of PDB 4wj7 Chain B

Receptor sequence
>4wj7B (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
SDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEH
DAVLSLSAYNVKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQ
DEACCLVILAAESKVAAEELCCLLGQVFQVVY
3D structure
PDB4wj7 Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
ChainB
Resolution2.753 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B P82 S83 H137 D138 I139 A140 A141 V142 S143 Y144 R146 A158 C210 F217 P23 S24 H78 D79 I80 A81 A82 V83 S84 Y85 R87 A99 C121 F128
External links
PDB RCSB:4wj7, PDBe:4wj7, PDBj:4wj7
PDBsum4wj7
PubMed25525273
UniProtQ9BSQ5|CCM2_HUMAN Cerebral cavernous malformations 2 protein (Gene Name=CCM2)

[Back to BioLiP]