Structure of PDB 4wit Chain B

Receptor sequence
>4witB (length=654) Species: 660122 (Fusarium vanettenii 77-13-4) [Search protein sequence]
GVDFVIHYKVPAAERDEAEAGFVQLIRALTTVGLATEVRHGENESLLVFV
KVASPDLFAKQVYRARLGDWLHGVRVSAPHNDIAQALQDEPVVEAERLRL
IYLMITKPHNEWKHVESIFPLHSHSFNKEWIKKWSSKYTLEQTDIDNIRD
KFGESVAFYFAFLRSYFRFLVIPSAFGFGAWLLLGQFSYLYALLCGLWSV
VFFEYWKKQEVDLAVQWGVRGVSSIQQSRPEFEWEHEAEDPITGEPVKVY
PPMKRVKTQLLQIPFALACVVALGALIVTCNSLEVFINEVYSGPGKQYLG
FLPTIFLVIGTPTISGVLMGAAEKLNAMENYATVDAHDAALIQKQFVLNF
MTSYMALFFTAFVYIPFGHILHPFLNFWRATAQTLTFSEKELPTREFQIN
PARISNQMFYFTVTAQIVNFATEVVVPYIKQQAFQAEFLQRVREECTLEE
YDVSGDYREMVMQFGYVAMFSVAWPLAACCFLVNNWVELRSDALKIAISS
RRPIPWRTDSIGPWLTALSFLSWLGSITSSAIVYLCSNASPLKAWGLLLS
ILFAEHFYLVVQLAVRFVLSKLDSPGLQKERKERFQTKKRLLQENLGQDA
AAAPGIEHSEKITREALEEEARQASIEMFWQRQRGMQETIEIGRRMIEQQ
LAAG
3D structure
PDB4wit X-ray structure of a calcium-activated TMEM16 lipid scramblase.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E452 D503 E506 E535 D539 E423 D456 E459 E488 D492
BS02 CA B N448 F449 E452 E506 E535 N419 F420 E423 E459 E488
Gene Ontology
Molecular Function
GO:0005254 chloride channel activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0032541 cortical endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4wit, PDBe:4wit, PDBj:4wit
PDBsum4wit
PubMed25383531
UniProtC7Z7K1

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