Structure of PDB 4w4z Chain B

Receptor sequence
>4w4zB (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
GNEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVME
PSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYY
ESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLS
KKGFYLAFQDVGACIALVSVRVFYKK
3D structure
PDB4w4z Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor.
ChainB
Resolution2.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Q71 T104 R106 P112 R162 M164 C191 Q44 T77 R79 P85 R135 M137 C164
External links
PDB RCSB:4w4z, PDBe:4w4z, PDBj:4w4z
PDBsum4w4z
PubMed25268696
UniProtP54764|EPHA4_HUMAN Ephrin type-A receptor 4 (Gene Name=EPHA4)

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