Structure of PDB 4v2y Chain B

Receptor sequence
>4v2yB (length=104) Species: 431944 (Magnetospirillum gryphiswaldense MSR-1) [Search protein sequence]
SIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRL
IGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLA
EGPA
3D structure
PDB4v2y Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
ChainB
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C24 C27 C90 C93 C5 C8 C71 C74
BS02 EF2 B N50 P51 F77 S78 W79 W85 W99 Y101 N31 P32 F58 S59 W60 W66 W80 Y82 BindingDB: Ki=4400nM,IC50=7800nM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4v2y, PDBe:4v2y, PDBj:4v2y
PDBsum4v2y
PubMed25448889
UniProtA4TVL0

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