Structure of PDB 4urm Chain B

Receptor sequence
>4urmB (length=195) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LEAARKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKD
NWIKVTDNGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGVGSSVVNALSQ
DLEVYVHRNETIYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTE
TTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEG
3D structure
PDB4urm Structures of Kibdelomycin Bound to Staphylococcus Aureus Gyrb and Pare Showed a Novel U-Shaped Binding Mode.
ChainB
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 XAM B I51 N54 E58 D81 I86 Q91 K93 I102 H107 A108 G109 G110 T173 I27 N30 E34 D57 I62 Q67 K69 I78 H83 A84 G85 G86 T137
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

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Molecular Function
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Biological Process
External links
PDB RCSB:4urm, PDBe:4urm, PDBj:4urm
PDBsum4urm
PubMed24992706
UniProtP0A0K8|GYRB_STAAU DNA gyrase subunit B (Gene Name=gyrB)

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