Structure of PDB 4une Chain B

Receptor sequence
>4uneB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFFTPKT
3D structure
PDB4une Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
ChainB
Resolution1.59 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B H5 L6 C7 V18 C19 R22 G23 F24 H5 L6 C7 V18 C19 R22 G23 F24
BS02 peptide B Q4 L6 Q4 L6
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4une, PDBe:4une, PDBj:4une
PDBsum4une
PubMed25286859
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

[Back to BioLiP]