Structure of PDB 4um9 Chain B

Receptor sequence
>4um9B (length=448) Species: 9606 (Homo sapiens) [Search protein sequence]
GCALGGTCEDCLLIGPQCAWCRCDTPANLLAKGCQLNFIENPVSQVEILK
NKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLY
YLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFV
KTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANI
DTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIV
CPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVH
LYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGL
NLSFTAICNNGTLFQHQKKCSHMKVGDTASFSVTVNIPHCERRSRHIIIK
PVGLGDALELLVSPECNCDCQVNSSKCHNGNGSFQCGVCACHPGPRCE
3D structure
PDB4um9 Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S125 A126 C180 I183 Y185 A217 N218 I219 T221 E223 S106 A107 C161 I164 Y166 A198 N199 I200 T202 E204
BS02 MG B S125 E223 S106 E204
BS03 CA B E162 N218 D220 P222 E223 E143 N199 D201 P203 E204
BS04 CA B S127 D130 D131 S108 D111 D112
External links
PDB RCSB:4um9, PDBe:4um9, PDBj:4um9
PDBsum4um9
PubMed25383667
UniProtP18564|ITB6_HUMAN Integrin beta-6 (Gene Name=ITGB6)

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