Structure of PDB 4um8 Chain B

Receptor sequence
>4um8B (length=423) Species: 9606 (Homo sapiens) [Search protein sequence]
GCALGGTCEDCLLIGPQCAWCARCDTPANLLAKGCQLNFIENPVSQVEIL
KNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDL
YYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPF
VKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISAN
IDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGI
VCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQV
HLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEG
LNLSFTAICNNGTLFQHQKKCSHMKVGDTASFSVTVNIPHCERRSRHIII
KPVGLGDALELLVSPECNCDCQK
3D structure
PDB4um8 Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
ChainB
Resolution2.852 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B D123 S125 E223 D254 D105 S107 E205 D236
BS02 CA B S127 D130 D131 K338 S109 D112 D113 K320
External links
PDB RCSB:4um8, PDBe:4um8, PDBj:4um8
PDBsum4um8
PubMed25383667
UniProtP18564|ITB6_HUMAN Integrin beta-6 (Gene Name=ITGB6)

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