Structure of PDB 4u0w Chain B

Receptor sequence
>4u0wB (length=243) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
HMNINKQSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQFGISRM
TVRQALSNLVNEGLLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMT
PGSRLIDYQLIDSTEELAAILGCGHPSSIHKITRVRLANDIPMAIESSHI
PFELAGELNESHFQSSIYDHIERYNSIPISRAKQELEPSAATTEEANILG
IQKGAPVLLIKRTTYLQNGTAFEHAKSVYRGDRYTFVHYMDRL
3D structure
PDB4u0w Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR.
ChainB
Resolution2.001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 16G B S88 F89 T90 R133 R135 E145 S165 I166 Y167 I209 R211 E222 Y228 S89 F90 T91 R134 R136 E146 S166 I167 Y168 I210 R212 E223 Y229 MOAD: Kd=1mM
PDBbind-CN: -logKd/Ki=3.00,Kd=1mM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4u0w, PDBe:4u0w, PDBj:4u0w
PDBsum4u0w
PubMed25564531
UniProtO34817|NAGR_BACSU HTH-type transcriptional repressor NagR (Gene Name=nagR)

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