Structure of PDB 4u0u Chain B

Receptor sequence
>4u0uB (length=323) Species: 9606 (Homo sapiens) [Search protein sequence]
AALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEEDKDII
QADYLYTRALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKVKKVMS
INSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYAVPGKSLEE
QNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYVDPVEAGRFR
TTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEFAALAHYKLV
YIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYHVLEAANEGD
VRPFIRFIAKCTETTLDTLLFAT
3D structure
PDB4u0u Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
ChainB
Resolution2.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.108: protein adenylyltransferase.
3.1.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B V316 H319 V360 D367 G368 N369 G370 R371 Y399 Y400 N407 V206 H209 V250 D257 G258 N259 G260 R261 Y289 Y290 N297
External links
PDB RCSB:4u0u, PDBe:4u0u, PDBj:4u0u
PDBsum4u0u
PubMed25435325
UniProtQ9BVA6|FICD_HUMAN Protein adenylyltransferase FICD (Gene Name=FICD)

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