Structure of PDB 4u0s Chain B

Receptor sequence
>4u0sB (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]
AALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEEDKDII
QADYLYTRALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKVKKVMS
INSALRRVMEETYYHHIYHTVAIGGNTLTLSEIRHILETRYAVPGKSLEE
QNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYVDPVEAGRFR
TTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEFAALAHYKLV
YIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYHVLEAANEGD
VRPFIRFIAKCTETTLDTLLFATT
3D structure
PDB4u0s Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
ChainB
Resolution2.49 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.108: protein adenylyltransferase.
3.1.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B H319 V360 H363 D367 G368 N369 G370 R371 Y399 Y400 L403 N407 H209 V250 H253 D257 G258 N259 G260 R261 Y289 Y290 L293 N297 MOAD: Kd=0.158uM
External links
PDB RCSB:4u0s, PDBe:4u0s, PDBj:4u0s
PDBsum4u0s
PubMed25435325
UniProtQ9BVA6|FICD_HUMAN Protein adenylyltransferase FICD (Gene Name=FICD)

[Back to BioLiP]