Structure of PDB 4tv1 Chain B

Receptor sequence
>4tv1B (length=233) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB4tv1 A structural perspective on nuclear receptors as targets of environmental compounds.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 L372 D538 L539 E542 I52 L66 D223 L224 E227
BS02 36M B E353 F404 E47 F98
External links
PDB RCSB:4tv1, PDBe:4tv1, PDBj:4tv1
PDBsum4tv1
PubMed25500867
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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