Structure of PDB 4tt3 Chain B

Receptor sequence
>4tt3B (length=486) Species: 9913 (Bos taurus) [Search protein sequence]
ILGADTSVDLEETGRVLSIGDGIARVHGLRNVQAEEMVEFSSGLKGMSLN
LEPDNVGVVVFGNDKLIKEGDIVKRTGAIVDVPVGEELLGRVVDALGNAI
DGKGPIGSKARRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRE
LIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRSTVAQ
LVKRLTDADAMKYTIVVSATASDAAPLQYLAPYSGCSMGEYFRDNGKHAL
IIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDA
FGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAI
NVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVADAATQQLLSRGVRL
TELLKQGQYSPMAIEEQVAVIYAGVRGYLDKLEPSKITKFENAFLSHVIS
QHQALLGKIRTDGKISEESDAKLKEIVTNFLAGFEA
3D structure
PDB4tt3 Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase.
ChainB
Resolution3.21 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K175 Q208 K209 R373
Catalytic site (residue number reindexed from 1) K160 Q193 K194 R358
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B Q172 T173 G174 K175 T176 S177 F357 R362 Q432 Q157 T158 G159 K160 T161 S162 F342 R347 Q408
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0032559 adenyl ribonucleotide binding
GO:0043531 ADP binding
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0006754 ATP biosynthetic process
GO:0015986 proton motive force-driven ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)
GO:0045267 proton-transporting ATP synthase, catalytic core

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4tt3, PDBe:4tt3, PDBj:4tt3
PDBsum4tt3
PubMed25049402
UniProtP19483|ATPA_BOVIN ATP synthase subunit alpha, mitochondrial (Gene Name=ATP5F1A)

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