Structure of PDB 4tpj Chain B

Receptor sequence
>4tpjB (length=450) Species: 211586 (Shewanella oneidensis MR-1) [Search protein sequence]
VSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSAC
AALIYVSPAIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTWFMF
SALGVIVVGNGLFKPNAGNLVRKIYESKIDSAFTIYYMAVNVGSTFSMLL
TPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMHKSLANYGSEP
DTRPVNKKSLAIVLALAALSVVASAIILEYEDVARVFVYAAGVAVLGIFF
HGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFQVFGTHLWTWS
PAQFQALNPIWIMVLSPVLAWIAAKFALGFAVVAIGFFIYGFAGQFAVNG
KTSSWVMIWGYASYSLGELLVSGLGLAMIARYMMGAYFVASGISQYLGGV
VANFASVPQDLVDPLQTLPVYTNLFNKLGVAAVVCTIIALAVLPLMRRLT
3D structure
PDB4tpj Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
ChainB
Resolution3.201 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R25 Y29 Y147 N151 S154 Y291 N329 E402 R18 Y22 Y137 N141 S144 Y270 N308 E368
Gene Ontology
Molecular Function
GO:0015333 peptide:proton symporter activity
GO:0022857 transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042937 tripeptide transmembrane transporter activity
GO:0071916 dipeptide transmembrane transporter activity
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0015833 peptide transport
GO:0035442 dipeptide transmembrane transport
GO:0042939 tripeptide transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:4tpj, PDBe:4tpj, PDBj:4tpj
PDBsum4tpj
PubMed25064511
UniProtQ8EHE6

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