Structure of PDB 4s3o Chain B

Receptor sequence
>4s3oB (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
TQPLSKTWELSLYELQRTPQEAITDLEIVVSPRSLHSELMCPICLDMLKN
TMTTKECLHRFCADCIITALRSNKECPTCRKKLVSKRSLRPDPNFDALIS
KIYPS
3D structure
PDB4s3o BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C51 C54 C72 C75 C41 C44 C62 C65
BS02 ZN B C67 H69 C87 C90 C57 H59 C76 C79
Gene Ontology
Cellular Component
GO:0000151 ubiquitin ligase complex

View graph for
Cellular Component
External links
PDB RCSB:4s3o, PDBe:4s3o, PDBj:4s3o
PDBsum4s3o
PubMed26151332
UniProtQ99496|RING2_HUMAN E3 ubiquitin-protein ligase RING2 (Gene Name=RNF2)

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