Structure of PDB 4s0t Chain B

Receptor sequence
>4s0tB (length=283) Species: 9606 (Homo sapiens) [Search protein sequence]
GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLESLQAPSREEAAK
WSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMST
YMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGT
WECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISL
FSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLT
ELRSINAQHTQRLLRIQDIHPFATPLMQELFGI
3D structure
PDB4s0t Developing Adnectins That Target SRC Co-Activator Binding to PXR: A Structural Approach toward Understanding Promiscuity of PXR.
ChainB
Resolution3.14 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 40U B M243 F288 W299 Y306 M323 H327 H407 M425 M95 F140 W151 Y158 M175 H179 H259 M277
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4s0t, PDBe:4s0t, PDBj:4s0t
PDBsum4s0t
PubMed25579995
UniProtO75469|NR1I2_HUMAN Nuclear receptor subfamily 1 group I member 2 (Gene Name=NR1I2)

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