Structure of PDB 4rkg Chain B

Receptor sequence
>4rkgB (length=46) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
KPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKE
3D structure
PDB4rkg Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B C525 R526 C527 N534 R543 P545 C4 R5 C6 N13 R22 P24 PDBbind-CN: Kd=25.7uM
BS02 ZN B C525 C527 C539 C544 C4 C6 C18 C23
BS03 ZN B C539 C553 C558 C561 C18 C32 C37 C40
BS04 ZN B C525 C546 C553 C556 C4 C25 C32 C35
Gene Ontology
Molecular Function
GO:0061630 ubiquitin protein ligase activity
Cellular Component
GO:0072487 MSL complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4rkg, PDBe:4rkg, PDBj:4rkg
PDBsum4rkg
PubMed25452275
UniProtP50534|MSL2_DROME E3 ubiquitin-protein ligase msl-2 (Gene Name=msl-2)

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