Structure of PDB 4rda Chain B

Receptor sequence
>4rdaB (length=196) Species: 9606 (Homo sapiens) [Search protein sequence]
DGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKN
LPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAA
LEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEK
AQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHS
3D structure
PDB4rda Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
ChainB
Resolution2.497 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SGN B K314 R369 K23 R78
BS02 SGN B H307 H376 V380 H16 H85 V89
BS03 SGN B R429 H430 H433 R138 H139 H142
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4rda, PDBe:4rda, PDBj:4rda
PDBsum4rda
PubMed25760599
UniProtP51693|APLP1_HUMAN Amyloid beta precursor like protein 1 (Gene Name=APLP1)

[Back to BioLiP]